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10.1111/imr.12258 http://scihub22266oqcxt.onion/10.1111/imr.12258 C4339213!4339213!25703552     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Immunol+Rev 2015 ; 264 (1): 60-73 Nephropedia Template TP {{tp|p=25703552|t=2015. Immunology studies in non-human primate models of tuberculosis |pdf=|usr=}}{{25703552}} gab.com Text Immunology studies in non-human primate models of tuberculosis JO: Immunol Rev http://www.kidney.de/pget.php?&tw=1&pmid=25703552 #FOAvip Non-human primates, primarily macaques, have been used to study tuberculosis for decades. However, in the last 15 years, this model has been refined substantially to allow careful investigations of the immune response and host-pathogen interactions in Mycobacterium tuberculosis infection. Low dose challenge with fully virulent strains in cynomolgus macaques result in the full clinical spectrum seen in humans, including latent and active infection. Reagents from humans are usually cross-reactive with macaques, further facilitating the use of this model system to study tuberculosis. Finally, macaques develop the spectrum of granuloma types seen in humans, providing a unique opportunity to investigate bacterial and host factors at the local (lung and lymph node) level. Here we review the past decade of immunology and pathology studies in macaque models of tuberculosis. Twit Text FOAVip Immunology studies in non-human primate models of tuberculosis ????Immunol Rev http://www.kidney.de/pget.php?&tw=1&pmid=25703552 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25703552 #FOAvip English Wikipedia <ref>{{Cite pmid|25703552}}</ref> Immunology studies in non-human primate models of tuberculosis #MMPMID25703552 Flynn JL; Gideon HP; Mattila JT; Lin PL Immunol Rev 2015[Mar]; 264 (1): 60-73 PMID25703552show ga Non-human primates, primarily macaques, have been used to study tuberculosis for decades. However, in the last 15 years, this model has been refined substantially to allow careful investigations of the immune response and host-pathogen interactions in Mycobacterium tuberculosis infection. Low dose challenge with fully virulent strains in cynomolgus macaques result in the full clinical spectrum seen in humans, including latent and active infection. Reagents from humans are usually cross-reactive with macaques, further facilitating the use of this model system to study tuberculosis. Finally, macaques develop the spectrum of granuloma types seen in humans, providing a unique opportunity to investigate bacterial and host factors at the local (lung and lymph node) level. Here we review the past decade of immunology and pathology studies in macaque models of tuberculosis. äImmunology studies in non-human primate models of tuberculosis (epmc).pdf DeepDyve Pubget Overpricing