The Molecular Basis of Rectal Cancer #MMPMID25733974
Shiller M; Boostrom S
Clin Colon Rectal Surg 2015[Mar]; 28 (1): 53-60 PMID25733974show ga
The majority of rectal carcinomas are sporadic in nature, and relevant testing for driver mutations to guide therapy is important. A thorough family history is necessary and helpful in elucidating a potential hereditary predilection for a patient's carcinoma. The adequate diagnosis of a heritable tendency toward colorectal carcinoma alters the management of a patient disease and permits the implementation of various surveillance algorithms as preventive measures.