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10.1007/s00109-014-1237-z http://scihub22266oqcxt.onion/10.1007/s00109-014-1237-z C4334719!4334719!25471483     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Mol+Med+(Berl) 2015 ; 93 (3): 263-9 Nephropedia Template TP {{tp|p=25471483|t=2015. Role of mitochondrial lipids in guiding fission and fusion |pdf=|usr=}}{{25471483}} gab.com Text Role of mitochondrial lipids in guiding fission and fusion JO: J Mol Med (Berl) http://www.kidney.de/pget.php?&tw=1&pmid=25471483 #FOAvip Clinically-important links have been established between mitochondrial function and cardiac physiology and disease in the context of signaling mechanisms, energy production, and muscle cell development. The proteins and processes that drive mitochondrial fusion and fission are now known to have emergent functions in intracellular calcium homeostasis, apoptosis, vascular smooth muscle cell proliferation, myofibril organization, and Notch-driven cell differentiation, all key issues in cardiac disease. Moreover, decreasing fission may confer protection against ischemic heart disease, particularly in the setting of obesity, diabetes, and heart failure. The importance of lipids in controlling mitochondrial fission and fusion is increasing becoming appreciated. Roles for the bulk and signaling lipids cardiolipin, phosphatidylethanolamine, phosphatidic acid, diacylglycerol, and lysophosphatidic acid and the enzymes that synthesize or metabolize them in the control of mitochondrial shape and function are reviewed here. A number of diseases have been linked to loss-of-function alleles for a subset of the enzymes, emphasizing the importance of the lipid environment in this context. Twit Text FOAVip Role of mitochondrial lipids in guiding fission and fusion ????J Mol Med (Berl) http://www.kidney.de/pget.php?&tw=1&pmid=25471483 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25471483 #FOAvip English Wikipedia <ref>{{Cite pmid|25471483}}</ref> Role of mitochondrial lipids in guiding fission and fusion #MMPMID25471483 Frohman MA J Mol Med (Berl) 2015[Mar]; 93 (3): 263-9 PMID25471483show ga Clinically-important links have been established between mitochondrial function and cardiac physiology and disease in the context of signaling mechanisms, energy production, and muscle cell development. The proteins and processes that drive mitochondrial fusion and fission are now known to have emergent functions in intracellular calcium homeostasis, apoptosis, vascular smooth muscle cell proliferation, myofibril organization, and Notch-driven cell differentiation, all key issues in cardiac disease. Moreover, decreasing fission may confer protection against ischemic heart disease, particularly in the setting of obesity, diabetes, and heart failure. The importance of lipids in controlling mitochondrial fission and fusion is increasing becoming appreciated. Roles for the bulk and signaling lipids cardiolipin, phosphatidylethanolamine, phosphatidic acid, diacylglycerol, and lysophosphatidic acid and the enzymes that synthesize or metabolize them in the control of mitochondrial shape and function are reviewed here. A number of diseases have been linked to loss-of-function alleles for a subset of the enzymes, emphasizing the importance of the lipid environment in this context. äRole of mitochondrial lipids in guiding fission and fusion (epmc).pdf DeepDyve Pubget Overpricing