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10.1037/neu0000118 http://scihub22266oqcxt.onion/10.1037/neu0000118 C4333113!4333113 !25133317     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25133317 &cmd=llinks): Failed to open stream: HTTP request failed! 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The posteromedial region of the default mode network shows attenuated task-induced deactivation in psychopathic prisoners |pdf=|usr=}}{{25133317 }} gab.com Text The posteromedial region of the default mode network shows attenuated task-induced deactivation in psychopathic prisoners JO: Neuropsychology http://www.kidney.de/pget.php?&tw=1&pmid=25133317 #FOAvip OBJECTIVE: Psychopathy is a personality disorder with symptoms that include lack of empathy or remorse, antisocial behavior, and excessive self-focus. Previous neuroimaging studies have linked psychopathy to dysfunction in the default mode network (DMN), a brain network that deactivates during externally focused tasks and is more engaged during self-referential processing. Specifically, the DMN has been found to remain relatively active in individuals with psychopathic tendencies during externally focused tasks, suggesting a failure to properly deactivate. However, the exact extent and nature of task-induced DMN dysfunction is poorly understood, including (a) the degree to which specific DMN subregions are affected in criminal psychopaths, and (b) how activity in these subregions relates to affective/interpersonal and antisocial/lifestyle traits of psychopathy. METHOD: We performed a group independent component analysis to assess DMN activation during a Go/NoGo task in a group of 22 high-psychopathy and 22 low-psychopathy prisoners. The identified group-level DMN was parcellated into 6 subregions, and group differences in task-induced activity were examined. RESULTS: In general, DMN subregions failed to deactivate beneath baseline in the high-psychopathy group. A group comparison with the low-psychopathy group localized this attenuated task-induced deactivation to the posteromedial cortical (mPC) region of the DMN. Moreover, multiple regression analyses revealed that activity in the mPC was associated with affective/interpersonal traits of psychopathy. CONCLUSION: These findings suggest that attenuated deactivation of the mPC subregion of the DMN is intrinsic to psychopathy, and is a pattern that may be more associated with affective psychopathic traits, including lack of concern for others. Twit Text FOAVip The posteromedial region of the default mode network shows attenuated task-induced deactivation in psychopathic prisoners ????Neuropsychology http://www.kidney.de/pget.php?&tw=1&pmid=25133317 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25133317 #FOAvip English Wikipedia <ref>{{Cite pmid|25133317 }}</ref> The posteromedial region of the default mode network shows attenuated task-induced deactivation in psychopathic prisoners #MMPMID25133317 Freeman SM ; Clewett DV ; Bennett CM ; Kiehl KA ; Gazzaniga MS ; Miller MB Neuropsychology 2015[May]; 29 (3 ): 493-500 PMID25133317 show ga OBJECTIVE: Psychopathy is a personality disorder with symptoms that include lack of empathy or remorse, antisocial behavior, and excessive self-focus. Previous neuroimaging studies have linked psychopathy to dysfunction in the default mode network (DMN), a brain network that deactivates during externally focused tasks and is more engaged during self-referential processing. Specifically, the DMN has been found to remain relatively active in individuals with psychopathic tendencies during externally focused tasks, suggesting a failure to properly deactivate. However, the exact extent and nature of task-induced DMN dysfunction is poorly understood, including (a) the degree to which specific DMN subregions are affected in criminal psychopaths, and (b) how activity in these subregions relates to affective/interpersonal and antisocial/lifestyle traits of psychopathy. METHOD: We performed a group independent component analysis to assess DMN activation during a Go/NoGo task in a group of 22 high-psychopathy and 22 low-psychopathy prisoners. The identified group-level DMN was parcellated into 6 subregions, and group differences in task-induced activity were examined. RESULTS: In general, DMN subregions failed to deactivate beneath baseline in the high-psychopathy group. A group comparison with the low-psychopathy group localized this attenuated task-induced deactivation to the posteromedial cortical (mPC) region of the DMN. Moreover, multiple regression analyses revealed that activity in the mPC was associated with affective/interpersonal traits of psychopathy. CONCLUSION: These findings suggest that attenuated deactivation of the mPC subregion of the DMN is intrinsic to psychopathy, and is a pattern that may be more associated with affective psychopathic traits, including lack of concern for others. |Antisocial Personality Disorder/*physiopathology [MESH] |Brain Mapping [MESH] |Brain/*physiopathology [MESH] |Criminals/*psychology [MESH] |Humans [MESH] |Magnetic Resonance Imaging [MESH] |Male [MESH] |Nerve Net/*physiopathology [MESH]The posteromedial region of the default mode network shows attenuated (epmc).pdf DeepDyve Pubget Overpricing