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10.1039/c4an01101e

http://scihub22266oqcxt.onion/10.1039/c4an01101e
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C4331244!4331244!25465248
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suck abstract from ncbi


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pmid25465248      Analyst 2015 ; 140 (5): 1391-410
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  • Trying to detect gas-phase ions? Understanding Ion Mobility Spectrometry: Part 2: Hyphenated Methods and Effects of Experimental Parameters #MMPMID25465248
  • Cumeras R; Figueras E; Davis C; Baumbach J; Gràcia I
  • Analyst 2015[Mar]; 140 (5): 1391-410 PMID25465248show ga
  • Ion Mobility Spectrometry (IMS) is a widely used and ?well-known? technique of ion separation in gaseous phase based on the differences of ion mobilities under an electric field. This technique has received increased interest over the last several decades as evidenced by the pace and advances of new IMS devices available. In this review we explore the hyphenated techniques that are used with IMS, especially mass spectrometry as identification approach and multi-capillary column as pre-separation approach. Also, we will pay special attention to the key figures of merit of the ion mobility spectrum and how data is treated, and the influences of the experimental parameters in both a conventional drift time IMS (DTIMS) and a miniaturized IMS also known as high Field Asymmetric IMS (FAIMS) in the planar configuration. The current review article is preceded by a companion review article which details the current instrumentation and to the sections that configures both a conventional DTIMS and FAIMS devices. Those reviews will give the reader an insightful view of the main characteristics and aspects of the IMS technique.
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