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10.1091/mbc.E14-08-1307

http://scihub22266oqcxt.onion/10.1091/mbc.E14-08-1307
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suck abstract from ncbi


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pmid25540431      Mol+Biol+Cell 2015 ; 26 (4): 740-50
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  • Clathrin-dependent entry and vesicle-mediated exocytosis define insulin transcytosis across microvascular endothelial cells #MMPMID25540431
  • Azizi PM; Zyla RE; Guan S; Wang C; Liu J; Bolz SS; Heit B; Klip A; Lee WL
  • Mol Biol Cell 2015[Feb]; 26 (4): 740-50 PMID25540431show ga
  • How insulin traverses the continuous endothelium of the microvasculature has been poorly studied. Development of a novel assay to measure insulin transcytosis reveals an unexpected role for clathrin in insulin transendothelial transport. Insulin transcytosis is dynamin and clathrin dependent but does not require cholesterol or caveolin-1.
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