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10.1128/AAC.04809-14

http://scihub22266oqcxt.onion/10.1128/AAC.04809-14
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C4325809!4325809 !25534744
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suck abstract from ncbi


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pmid25534744
      Antimicrob+Agents+Chemother 2015 ; 59 (3 ): 1802-5
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  • Activity of eravacycline against Enterobacteriaceae and Acinetobacter baumannii, including multidrug-resistant isolates, from New York City #MMPMID25534744
  • Abdallah M ; Olafisoye O ; Cortes C ; Urban C ; Landman D ; Quale J
  • Antimicrob Agents Chemother 2015[Mar]; 59 (3 ): 1802-5 PMID25534744 show ga
  • Eravacycline demonstrated in vitro activity against a contemporary collection of more than 4,000 Gram-negative pathogens from New York City hospitals, with MIC50/MIC90 values, respectively, for Escherichia coli of 0.12/0.5 ?g/ml, Klebsiella pneumoniae of 0.25/1 ?g/ml, Enterobacter aerogenes of 0.25/1 ?g/ml, Enterobacter cloacae 0.5/1 ?g/ml, and Acinetobacter baumannii of 0.5/1 ?g/ml. Activity was retained against multidrug-resistant isolates, including those expressing KPC and OXA carbapenemases. For A. baumannii, eravacycline MICs correlated with increased expression of the adeB gene.
  • |Acinetobacter Infections/*drug therapy/microbiology [MESH]
  • |Acinetobacter baumannii/*drug effects/isolation & purification [MESH]
  • |Anti-Bacterial Agents/*therapeutic use [MESH]
  • |Drug Resistance, Multiple, Bacterial/*drug effects [MESH]
  • |Enterobacteriaceae Infections/*drug therapy/microbiology [MESH]
  • |Enterobacteriaceae/*drug effects/isolation & purification [MESH]
  • |Hospitals [MESH]
  • |Humans [MESH]
  • |Microbial Sensitivity Tests/methods [MESH]
  • |New York City [MESH]


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