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Effectiveness of phosphodiesterase-5 inhibitor therapy for portopulmonary hypertension #MMPMID25522305
Fisher JH; Johnson SR; Chau C; Kron AT; Granton JT
Can Respir J 2015[Jan]; 22 (1): 42-6 PMID25522305show ga
Portopulmonary hypertension (PoPH), a serious complication of chronic liver disease, is associated with significant morbidity and mortality. Prompted, in part, by a lack of data from the PoPH population, this single-centre, retrospective study investigated the efficacy of phosphodiesterase-5 inhibitor therapy with respect to hemodynamic measures, including pulmonary vascular resistance and Fick cardiac output, in 25 PoPH patients at the University Health Network in Toronto, Ontario.