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10.1016/j.gtc.2014.11.013

http://scihub22266oqcxt.onion/10.1016/j.gtc.2014.11.013
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suck abstract from ncbi


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pmid25667031      Gastroenterol+Clin+North+Am 2015 ; 44 (1): 169-84
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  • Gastric arrhythmias in gastroparesis: low and high resolution mapping of gastric electrical activity #MMPMID25667031
  • O?Grady G; Abell T
  • Gastroenterol Clin North Am 2015[Mar]; 44 (1): 169-84 PMID25667031show ga
  • Gastric arrhythmias occur in gastroparesis, however, their meaning and significance has been debated. Recently, an improved understanding of dysrhythmia has begun to emerge, informed by cellular, physiological, and engineering progress. This review discusses these advances and considers clinical applications. An important foundation has been defining histopathological abnormalities in gastroparesis. The finding that interstitial cells of Cajal are depleted and injured provides mechanisms for arrhythmogenesis in gastroparesis, and has reinvigorated clinical interest in electrical diagnostics. Electrogastrography (EGG) has been the dominant method to date, demonstrating consistent associations between arrhythmias and gastroparesis, however, is fundamentally limited by its summative nature, low signal quality, and incomplete sensitivity and specificity. Recently, high-resolution (HR; multi-electrode) mapping has emerged, providing superior spatial data on arrhythmic patterns and mechanisms, and enabling new insights and classifications. However, HR mapping is currently limited by invasiveness, and low-resolution approaches are being assessed as bridging techniques until this limitation is overcome.
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