Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Ophthalmology 2014 ; 121 (4): 877-82 Nephropedia Template TP
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Incidence, Types, and Lifetime Risk of Adult-onset Strabismus #MMPMID24321142
Ophthalmology 2014[Apr]; 121 (4): 877-82 PMID24321142show ga
Objective: To describe the incidence and types of adult-onset strabismus in a geographically defined population. Design: Retrospectively reviewed population-based cohort. Participants: All adult (?19 years of age) residents of Olmsted County, Minnesota diagnosed with new-onset adult strabismus from January 1, 1985, through December 31, 2004. Methods: The medical records of all potential cases identified by the resources of the Rochester Epidemiology Project were reviewed. Main Outcome Measures: Incidence rates for adult-onset strabismus and its types. Results: Seven hundred fifty-three cases of new-onset adult strabismus were identified during the twenty-year period, yielding an annual age- and gender-adjusted incidence rate of 54.1 cases (95% confidence interval 50.2?58.0) per 100,000 individuals ? 19 years of age. The four most common types of new-onset strabismus were paralytic (44.2% of cases), convergence insufficiency (15.7%), small angle hypertropia (13.3%), and divergence insufficiency (10.6%). The incidence of adult-onset strabismus overall and its four most common forms significantly increased with age (p<0.001 for all), with a peak incidence in the eighth decade of life. The lifetime risk of being diagnosed with adult-onset strabismus was 4.0% in females and 3.9% in males. Conclusions: Paralytic strabismus was the most common subtype of new-onset adult strabismus in this population-based cohort. All of the most common forms of adult-onset strabismus increased with age, especially after the sixth decade of life. Further characterization of strabismus types found in this study is warranted to better define this common disorder.