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10.1073/pnas.1424012112 http://scihub22266oqcxt.onion/10.1073/pnas.1424012112 C4313835!4313835!25583473     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2015 ; 112 (4): 1131-6 Nephropedia Template TP {{tp|p=25583473|t=2015. The butterfly effect in cancer: A single base mutation can remodel the cell |pdf=|usr=}}{{25583473}} gab.com Text The butterfly effect in cancer: A single base mutation can remodel the cell JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25583473 #FOAvip A single base substitution in one allele of the PIK3CA gene (encoding the catalytic subunit p110? of PI3K) in a human breast epithelial cell induces a gene expression profile that closely resembles the gene expression profile of basal breast cancer. The mutation also causes extensive remodeling of gene signatures that are not known to be connected to the activity of PI3K. The data show that a cancer-specific mutation that induces a gain of function in PI3K has an unexpectedly deep and broad impact on the phenotypic properties of the cell. Twit Text FOAVip The butterfly effect in cancer: A single base mutation can remodel the cell ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25583473 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25583473 #FOAvip English Wikipedia <ref>{{Cite pmid|25583473}}</ref> The butterfly effect in cancer: A single base mutation can remodel the cell #MMPMID25583473 Hart JR; Zhang Y; Liao L; Ueno L; Du L; Jonkers M; Yates JR; Vogt PK Proc Natl Acad Sci U S A 2015[Jan]; 112 (4): 1131-6 PMID25583473show ga A single base substitution in one allele of the PIK3CA gene (encoding the catalytic subunit p110? of PI3K) in a human breast epithelial cell induces a gene expression profile that closely resembles the gene expression profile of basal breast cancer. The mutation also causes extensive remodeling of gene signatures that are not known to be connected to the activity of PI3K. The data show that a cancer-specific mutation that induces a gain of function in PI3K has an unexpectedly deep and broad impact on the phenotypic properties of the cell. äThe butterfly effect in cancer: A single base mutation can remodel the(epmc).pdf DeepDyve Pubget Overpricing