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10.1091/mbc.E14-10-1477

http://scihub22266oqcxt.onion/10.1091/mbc.E14-10-1477
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C4310740!4310740!25473116
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suck abstract from ncbi


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pmid25473116      Mol+Biol+Cell 2015 ; 26 (3): 495-505
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  • A novel role for WAVE1 in controlling actin network growth rate and architecture #MMPMID25473116
  • Sweeney MO; Collins A; Padrick SB; Goode BL
  • Mol Biol Cell 2015[Feb]; 26 (3): 495-505 PMID25473116show ga
  • A novel functional role for WAVE1 is found that is lacking in N-WASP and WAVE2. Through its unique WH2 domain, WAVE1 dramatically reduces the rate of actin filament elongation independently of its interactions with the Arp2/3 complex. These findings help explain how cells build actin networks with distinct geometries and growth rates.
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