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2014 ; 9
(3
): e131-e135
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gab.com Text
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English Wikipedia
Association of egg consumption and calcified atherosclerotic plaque in the
coronary arteries: the NHLBI Family Heart Study
#MMPMID25642410
Robbins JM
; Petrone AB
; Ellison RC
; Hunt SC
; Carr JJ
; Heiss G
; Arnett DK
; Gaziano JM
; Djoussé L
ESPEN J
2014[Jun]; 9
(3
): e131-e135
PMID25642410
show ga
BACKGROUND AND AIMS: Eggs are a ubiquitous and important source of dietary
cholesterol and nutrients, yet their relationship to coronary heart disease (CHD)
remains unclear. While some data have suggested a positive association between
egg consumption and CHD, especially among diabetic subjects, limited data exist
on the influence of egg consumption on subclinical disease. Thus, we sought to
examine whether egg consumption is associated with calcified atherosclerotic
plaques in the coronary arteries. METHODS: In a cross-sectional design, we
studied 1848 participants of the NHLBI Family Heart Study without known CHD. Egg
consumption was assessed by a semi-quantitative food frequency questionnaire and
coronary-artery calcium (CAC) was measured by cardiac CT. We defined prevalent
CAC using an Agatston score of at least 100 and fitted generalized estimating
equations to calculate prevalence odds ratios of CAC. RESULTS: Mean age was 56.5
years and 41% were male. Median consumption of eggs was 1/week. There was no
association between frequency of egg consumption and prevalent CAC. Odds ratios
(95% CI) for CAC were 1.0 (reference), 0.95 (0.66-1.38), 0.94 (0.63-1.40), and
0.90 (0.57-1.42) for egg consumption of almost never, 1-3 times per month, once
per week, and 2+ times per week, respectively (p for trend 0.66), adjusting for
age, sex, BMI, smoking, alcohol, physical activity, income, field center, total
calories, and bacon. Additional control for hypertension and diabetes mellitus,
or restricting the analysis to subjects with diabetes mellitus or fasting glucose
>126 mg/dL did not alter the findings. CONCLUSIONS: These data do not provide
evidence for an association between egg consumption and prevalent CAC in adult
men and women.