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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Curr+Opin+Genet+Dev 2014 ; 29 (ä): 120-32 Nephropedia Template TP
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The peopling of the African continent and the diaspora into the new world #MMPMID25461616
Campbell MC; Hirbo JB; Townsend JP; Tishkoff SA
Curr Opin Genet Dev 2014[Dec]; 29 (ä): 120-32 PMID25461616show ga
Africa is the birthplace of anatomically modern humans, and is the geographic origin of human migration across the globe within the last 100,000 years. The history of African populations has consisted of a number of demographic events that have influenced patterns of genetic and phenotypic variation across the continent. With the increasing amount of genomic data and corresponding developments in computational methods, researchers are able to explore long-standing evolutionary questions, expanding our understanding of human history within and outside of Africa. This review will summarize some of the recent findings regarding African demographic history, including the African Diaspora, and will briefly explore their implications for disease susceptibility in populations of African descent.