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10.1073/pnas.1404481112 http://scihub22266oqcxt.onion/10.1073/pnas.1404481112 C4299241!4299241!25540415     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2015 ; 112 (2): 326-31 Nephropedia Template TP {{tp|p=25540415|t=2015. Energetic basis for the molecular-scale organization of bone |pdf=|usr=}}{{25540415}} gab.com Text Energetic basis for the molecular-scale organization of bone JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25540415 #FOAvip The remarkable mechanical properties of bone are determined by the organization and strength of binding at the mineral?collagen interface. Although the process through which collagen becomes mineralized has been extensively studied, little is known about the mechanisms or energetics that underlie the organization of this mineral?matrix composite. Combining molecular-scale imaging and analyses of collagen adsorption on four bone-related calcium phosphate phases, single-molecule force measurements and molecular simulations of collagen binding to hydroxyapatite, and electron microscopy analyses of bone and dentine, we determine the magnitude and chemistry of collagen?hydroxyapatite binding and show that calcium-deficient apatite is the only phase consistent with observed structural relationships. Twit Text FOAVip Energetic basis for the molecular-scale organization of bone ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25540415 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25540415 #FOAvip English Wikipedia <ref>{{Cite pmid|25540415}}</ref> Energetic basis for the molecular-scale organization of bone #MMPMID25540415 Tao J; Battle KC; Pan H; Salter EA; Chien YC; Wierzbicki A; De Yoreo JJ Proc Natl Acad Sci U S A 2015[Jan]; 112 (2): 326-31 PMID25540415show ga The remarkable mechanical properties of bone are determined by the organization and strength of binding at the mineral?collagen interface. Although the process through which collagen becomes mineralized has been extensively studied, little is known about the mechanisms or energetics that underlie the organization of this mineral?matrix composite. Combining molecular-scale imaging and analyses of collagen adsorption on four bone-related calcium phosphate phases, single-molecule force measurements and molecular simulations of collagen binding to hydroxyapatite, and electron microscopy analyses of bone and dentine, we determine the magnitude and chemistry of collagen?hydroxyapatite binding and show that calcium-deficient apatite is the only phase consistent with observed structural relationships. äEnergetic basis for the molecular-scale organization of bone (epmc).pdf DeepDyve Pubget Overpricing