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2010 ; 1
(2
): 108-12
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English Wikipedia
Clinical Outcomes following the Microfracture Procedure for Chondral Defects of
the Knee: A Longitudinal Data Analysis
#MMPMID26069541
Miller BS
; Briggs KK
; Downie B
; Steadman JR
Cartilage
2010[Apr]; 1
(2
): 108-12
PMID26069541
show ga
The purpose of this study was to evaluate long-term outcome, following
microfracture of the knee in a large patient group, using a random-effect model
for longitudinal data analysis. There were 350 subjects (males, 55%; females,
65%) who underwent knee microfracture by a single surgeon between 1992 and 2002.
Mean age was 48 years (range, 12-76 years). Subjective questionnaires were
collected from patients at 1 year postsurgery and each consecutive year
thereafter. Of treated chondral lesions, 53% were traumatic lesions, and 47% were
degenerative. Average initial follow-up was 4 years (range, 1-12 years). Outcome
variables included Lysholm score and Tegner activity scale. Analysis showed that
Lysholm score improved during the first 2 years following microfracture. After 2
years, the score remained steady with a slight decline but remained above
preoperative level through the study period. There was no significant difference
in the improvement of outcome over time between men and women (P > 0.05). There
was no significant difference in improvement of outcome over time between
degenerative and traumatic chondral lesions (P > 0.05). Subjects with traumatic
lesions demonstrated a significant difference in trajectory of Lysholm scores
over time by age (?45 years, >45 years) (P = 0.04). This study showed that there
was no difference in improvement in outcome following microfracture between men
and women or between degenerative and traumatic chondral lesions. However, there
were age-dependent differences in the improvement in outcome over time.