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Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Bioinformatics 2014 ; 30 (23): 3440-2 Nephropedia Template TP
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ProtocolNavigator: emulation-based software for the design, documentation and reproduction biological experiments #MMPMID25150250
Khan IA; Fraser A; Bray MA; Smith PJ; White NS; Carpenter AE; Errington RJ
Bioinformatics 2014[Dec]; 30 (23): 3440-2 PMID25150250show ga
Motivation: Experimental reproducibility is fundamental to the progress of science. Irreproducible research decreases the efficiency of basic biological research and drug discovery and impedes experimental data reuse. A major contributing factor to irreproducibility is difficulty in interpreting complex experimental methodologies and designs from written text and in assessing variations among different experiments. Current bioinformatics initiatives either are focused on computational research reproducibility (i.e. data analysis) or laboratory information management systems. Here, we present a software tool, ProtocolNavigator, which addresses the largely overlooked challenges of interpretation and assessment. It provides a biologist-friendly open-source emulation-based tool for designing, documenting and reproducing biological experiments.Availability and implementation: ProtocolNavigator was implemented in Python 2.7, using the wx module to build the graphical user interface. It is a platform-independent software and freely available from http://protocolnavigator.org/index.html under the GPL v2 license.Contact:wpciak@cf.ac.ukSupplementary information:Supplementary data are available at Bioinformatics online.