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2014 ; 30
(23
): 3440-2
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ProtocolNavigator: emulation-based software for the design, documentation and
reproduction biological experiments
#MMPMID25150250
Khan IA
; Fraser A
; Bray MA
; Smith PJ
; White NS
; Carpenter AE
; Errington RJ
Bioinformatics
2014[Dec]; 30
(23
): 3440-2
PMID25150250
show ga
MOTIVATION: Experimental reproducibility is fundamental to the progress of
science. Irreproducible research decreases the efficiency of basic biological
research and drug discovery and impedes experimental data reuse. A major
contributing factor to irreproducibility is difficulty in interpreting complex
experimental methodologies and designs from written text and in assessing
variations among different experiments. Current bioinformatics initiatives either
are focused on computational research reproducibility (i.e. data analysis) or
laboratory information management systems. Here, we present a software tool,
ProtocolNavigator, which addresses the largely overlooked challenges of
interpretation and assessment. It provides a biologist-friendly open-source
emulation-based tool for designing, documenting and reproducing biological
experiments. AVAILABILITY AND IMPLEMENTATION: ProtocolNavigator was implemented
in Python 2.7, using the wx module to build the graphical user interface. It is a
platform-independent software and freely available from
http://protocolnavigator.org/index.html under the GPL v2 license.