Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25614715
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25614715
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Mediators+Inflamm
2014 ; 2014
(ä): 921054
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
CD206+ cell number differentiates influenza A (H1N1)pdm09 from seasonal influenza
A virus in fatal cases
#MMPMID25614715
Rodriguez-Ramirez HG
; Salinas-Carmona MC
; Barboza-Quintana O
; Melo-de la Garza A
; Ceceņas-Falcon LA
; Rangel-Martinez LM
; Rosas-Taraco AG
Mediators Inflamm
2014[]; 2014
(ä): 921054
PMID25614715
show ga
In 2009, a new influenza A (H1N1) virus affected many persons around the world.
There is an urgent need for finding biomarkers to distinguish between influenza A
(H1N1)pdm09 and seasonal influenza virus. We investigated these possible
biomarkers in the lung of fatal cases of confirmed influenza A (H1N1)pdm09.
Cytokines (inflammatory and anti-inflammatory) and cellular markers (macrophages
and lymphocytes subpopulation markers) were analyzed in lung tissue from both
influenza A (H1N1)pdm09 and seasonal influenza virus. High levels of IL-17,
IFN-?, and TNF-? positive cells were identical in lung tissue from the influenza
A (H1N1)pdm09 and seasonal cases when compared with healthy lung tissue (P <
0.05). Increased IL-4+ cells, and CD4+ and CD14+ cells were also found in high
levels in both influenza A (H1N1)pdm09 and seasonal influenza virus (P < 0.05).
Low levels of CD206+ cells (marker of alternatively activated macrophages marker
in lung) were found in influenza A (H1N1)pdm09 when compared with seasonal
influenza virus (P < 0.05), and the ratio of CD206/CD14+ cells was 2.5-fold
higher in seasonal and noninfluenza group compared with influenza A (H1N1)pdm09
(P < 0.05). In conclusion, CD206+ cells differentiate between influenza A
(H1N1)pdm09 and seasonal influenza virus in lung tissue of fatal cases.
|Adult
[MESH]
|Aged
[MESH]
|Biomarkers/metabolism
[MESH]
|CD4 Antigens/metabolism
[MESH]
|Female
[MESH]
|Humans
[MESH]
|Inflammation
[MESH]
|Influenza A Virus, H1N1 Subtype/*classification
[MESH]