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10.1523/JNEUROSCI.3613-14.2015 http://scihub22266oqcxt.onion/10.1523/JNEUROSCI.3613-14.2015 C4293411!4293411!25589751     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Neurosci 2015 ; 35 (2): 559-70 Nephropedia Template TP {{tp|p=25589751|t=2015. Vertebrate Epidermal Cells Are Broad-Specificity Phagocytes That Clear Sensory Axon Debris |pdf=|usr=}}{{25589751}} gab.com Text Vertebrate Epidermal Cells Are Broad-Specificity Phagocytes That Clear Sensory Axon Debris JO: J Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=25589751 #FOAvip Cellular debris created by developmental processes or injury must be cleared by phagocytic cells to maintain and repair tissues. Cutaneous injuries damage not only epidermal cells but also the axonal endings of somatosensory (touch-sensing) neurons, which must be repaired to restore the sensory function of the skin. Phagocytosis of neuronal debris is usually performed by macrophages or other blood-derived professional phagocytes, but we have found that epidermal cells phagocytose somatosensory axon debris in zebrafish. Live imaging revealed that epidermal cells rapidly internalize debris into dynamic phosphatidylinositol 3-monophosphate-positive phagosomes that mature into phagolysosomes using a pathway similar to that of professional phagocytes. Epidermal cells phagocytosed not only somatosensory axon debris but also debris created by injury to other peripheral axons that were mislocalized to the skin, neighboring skin cells, and macrophages. Together, these results identify vertebrate epidermal cells as broad-specificity phagocytes that likely contribute to neural repair and wound healing. Twit Text FOAVip Vertebrate Epidermal Cells Are Broad-Specificity Phagocytes That Clear Sensory Axon Debris ????J Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=25589751 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25589751 #FOAvip English Wikipedia <ref>{{Cite pmid|25589751}}</ref> Vertebrate Epidermal Cells Are Broad-Specificity Phagocytes That Clear Sensory Axon Debris #MMPMID25589751 Rasmussen JP; Sack GS; Martin SM; Sagasti A J Neurosci 2015[Jan]; 35 (2): 559-70 PMID25589751show ga Cellular debris created by developmental processes or injury must be cleared by phagocytic cells to maintain and repair tissues. Cutaneous injuries damage not only epidermal cells but also the axonal endings of somatosensory (touch-sensing) neurons, which must be repaired to restore the sensory function of the skin. Phagocytosis of neuronal debris is usually performed by macrophages or other blood-derived professional phagocytes, but we have found that epidermal cells phagocytose somatosensory axon debris in zebrafish. Live imaging revealed that epidermal cells rapidly internalize debris into dynamic phosphatidylinositol 3-monophosphate-positive phagosomes that mature into phagolysosomes using a pathway similar to that of professional phagocytes. Epidermal cells phagocytosed not only somatosensory axon debris but also debris created by injury to other peripheral axons that were mislocalized to the skin, neighboring skin cells, and macrophages. Together, these results identify vertebrate epidermal cells as broad-specificity phagocytes that likely contribute to neural repair and wound healing. äVertebrate Epidermal Cells Are Broad-Specificity Phagocytes That Clear(epmc).pdf DeepDyve Pubget Overpricing