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10.4161/21624011.2014.955685

http://scihub22266oqcxt.onion/10.4161/21624011.2014.955685
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C4292417!4292417!25941619
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suck abstract from ncbi


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pmid25941619      Oncoimmunology 2014 ; 3 (9): ä
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  • Vitamin B6 improves the immunogenicity of cisplatin-induced cell death #MMPMID25941619
  • Aranda F; Bloy N; Galluzzi L; Kroemer G; Senovilla L
  • Oncoimmunology 2014[]; 3 (9): ä PMID25941619show ga
  • We have recently demonstrated that pyridoxine, a precursor of vitamin B6, increases the immunogenicity of non-small cell lung carcinoma (NSCLC) cells succumbing to cisplatin (cis-diamminedichloroplatinum(II), CDDP). Accordingly, pyridoxine promoted the antineoplastic activity of CDDP in NSCLC-bearing mice only in the presence of an intact immune system. These findings may have implications for the development of novel strategies to circumvent CDDP resistance.
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