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10.4161/21624011.2014.947891

http://scihub22266oqcxt.onion/10.4161/21624011.2014.947891
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C4292209!4292209!25610735
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suck abstract from ncbi


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pmid25610735      Oncoimmunology 2014 ; 3 (7): ä
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  • COMMD1 regulates inflammation and colitis-associated cancer progression #MMPMID25610735
  • Li H; Burstein E
  • Oncoimmunology 2014[]; 3 (7): ä PMID25610735show ga
  • NF-?B is a master transcriptional regulator of inflammation that plays an important role in oncogenesis, particularly in tumors that arise in the context of inflammation. Copper metabolism MURR1 domain-containing 1 (COMMD1) is a negative regulator of NF-?B. Recent genetic-based studies in both mice and human patients indicate that COMMD1 has an important role in controlling intestinal inflammation and constraining progression to colitis-associated cancer.
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