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10.1586/14737175.2014.918849 http://scihub22266oqcxt.onion/10.1586/14737175.2014.918849 C4288738!4288738!24831349     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Expert+Rev+Neurother 2014 ; 14 (6): 679-85 Nephropedia Template TP {{tp|p=24831349|t=2014. Acrolein detection: potential theranostic utility in multiple sclerosis and spinal cord injury |pdf=|usr=}}{{24831349}} gab.com Text Acrolein detection: potential theranostic utility in multiple sclerosis and spinal cord injury JO: Expert Rev Neurother http://www.kidney.de/pget.php?&tw=1&pmid=24831349 #FOAvip Oxidative stress has been implicated as a major pathological process underlying CNS disease and trauma. More specifically, acrolein, an unsaturated aldehyde, produced by way of lipid peroxidation, has been shown to play a crucial role in initiating and perpetuating detrimental effects associated with multiple sclerosis and spinal cord injury. In light of these findings, quantification of acrolein levels both systemically and locally could allow for the use of acrolein as a biomarker to aid in diagnosis and guide treatment regimens. The three main approaches currently available are acrolein derivatization followed byLC/GC?MS, application of an acrolein antibody and subsequent immunoblotting, and the 3-hydroxypropylmercapturic acid-based method. Of these three strategies, the 3-hydroxypropylmercapturic acid-based method is the least invasive allowing for rapid translation of acrolein detection into a clinical setting. Twit Text FOAVip Acrolein detection: potential theranostic utility in multiple sclerosis and spinal cord injury ????Expert Rev Neurother http://www.kidney.de/pget.php?&tw=1&pmid=24831349 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24831349 #FOAvip English Wikipedia <ref>{{Cite pmid|24831349}}</ref> Acrolein detection: potential theranostic utility in multiple sclerosis and spinal cord injury #MMPMID24831349 Tully M; Zheng L; Shi R Expert Rev Neurother 2014[Jun]; 14 (6): 679-85 PMID24831349show ga Oxidative stress has been implicated as a major pathological process underlying CNS disease and trauma. More specifically, acrolein, an unsaturated aldehyde, produced by way of lipid peroxidation, has been shown to play a crucial role in initiating and perpetuating detrimental effects associated with multiple sclerosis and spinal cord injury. In light of these findings, quantification of acrolein levels both systemically and locally could allow for the use of acrolein as a biomarker to aid in diagnosis and guide treatment regimens. The three main approaches currently available are acrolein derivatization followed byLC/GC?MS, application of an acrolein antibody and subsequent immunoblotting, and the 3-hydroxypropylmercapturic acid-based method. Of these three strategies, the 3-hydroxypropylmercapturic acid-based method is the least invasive allowing for rapid translation of acrolein detection into a clinical setting. äAcrolein detection: potential theranostic utility in multiple sclerosi(epmc).pdf DeepDyve Pubget Overpricing