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10.1002/bies.201400011 http://scihub22266oqcxt.onion/10.1002/bies.201400011 C4286338!4286338!25220035     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Bioessays 2014 ; 36 (12): 1195-203 Nephropedia Template TP {{tp|p=25220035|t=2014. How cells explore shape space: A quantitative statistical perspective of cellular morphogenesis |pdf=|usr=}}{{25220035}} gab.com Text How cells explore shape space: A quantitative statistical perspective of cellular morphogenesis JO: Bioessays http://www.kidney.de/pget.php?&tw=1&pmid=25220035 #FOAvip Through statistical analysis of datasets describing single cell shape following systematic gene depletion, we have found that the morphological landscapes explored by cells are composed of a small number of attractor states. We propose that the topology of these landscapes is in large part determined by cell-intrinsic factors, such as biophysical constraints on cytoskeletal organization, and reflect different stable signaling and/or transcriptional states. Cell-extrinsic factors act to determine how cells explore these landscapes, and the topology of the landscapes themselves. Informational stimuli primarily drive transitions between stable states by engaging signaling networks, while mechanical stimuli tune, or even radically alter, the topology of these landscapes. As environments fluctuate, the topology of morphological landscapes explored by cells dynamically adapts to these fluctuations. Finally we hypothesize how complex cellular and tissue morphologies can be generated from a limited number of simple cell shapes. Twit Text FOAVip How cells explore shape space: A quantitative statistical perspective of cellular morphogenesis ????Bioessays http://www.kidney.de/pget.php?&tw=1&pmid=25220035 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25220035 #FOAvip English Wikipedia <ref>{{Cite pmid|25220035}}</ref> How cells explore shape space: A quantitative statistical perspective of cellular morphogenesis #MMPMID25220035 Yin Z; Sailem H; Sero J; Ardy R; Wong ST; Bakal C Bioessays 2014[Dec]; 36 (12): 1195-203 PMID25220035show ga Through statistical analysis of datasets describing single cell shape following systematic gene depletion, we have found that the morphological landscapes explored by cells are composed of a small number of attractor states. We propose that the topology of these landscapes is in large part determined by cell-intrinsic factors, such as biophysical constraints on cytoskeletal organization, and reflect different stable signaling and/or transcriptional states. Cell-extrinsic factors act to determine how cells explore these landscapes, and the topology of the landscapes themselves. Informational stimuli primarily drive transitions between stable states by engaging signaling networks, while mechanical stimuli tune, or even radically alter, the topology of these landscapes. As environments fluctuate, the topology of morphological landscapes explored by cells dynamically adapts to these fluctuations. Finally we hypothesize how complex cellular and tissue morphologies can be generated from a limited number of simple cell shapes. äHow cells explore shape space: A quantitative statistical perspective (epmc).pdf DeepDyve Pubget Overpricing