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10.1093/eurheartj/ehu319

http://scihub22266oqcxt.onion/10.1093/eurheartj/ehu319
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C4286319!4286319!25142968
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suck abstract from ncbi


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pmid25142968      Eur+Heart+J 2015 ; 36 (1): 39-48b
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  • Anacetrapib reduces progression of atherosclerosis, mainly by reducing non-HDL-cholesterol, improves lesion stability and adds to the beneficial effects of atorvastatin #MMPMID25142968
  • Kühnast S; van der Tuin SJ; van der Hoorn JW; van Klinken JB; Simic B; Pieterman E; Havekes LM; Landmesser U; Lüscher TF; Willems van Dijk K; Rensen PC; Jukema JW; Princen HM
  • Eur Heart J 2015[Jan]; 36 (1): 39-48b PMID25142968show ga
  • The present study is the first intervention study in a well-established, translational mouse model for hyperlipidaemia and atherosclerosis showing that anacetrapib dose-dependently reduces atherosclerosis development and adds to the anti-atherogenic effects of atorvastatin. This effect is mainly ascribed to the reduction in non-HDL-C despite a remarkable increase in HDL-C and without affecting HDL functionality. In addition, anacetrapib improves lesion stability.
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