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10.1016/j.molimm.2014.10.017 http://scihub22266oqcxt.onion/10.1016/j.molimm.2014.10.017 C4282836!4282836 !25467802     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25467802 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Mol+Immunol 2015 ; 64 (1 ): 9-17 Nephropedia Template TP {{tp|p=25467802 |t=2015. Alternative complement pathway component Factor D contributes to efficient clearance of tissue debris following acute CCl?-induced injury |pdf=|usr=}}{{25467802 }} gab.com Text Alternative complement pathway component Factor D contributes to efficient clearance of tissue debris following acute CCl -induced injury JO: Mol Immunol http://www.kidney.de/pget.php?&tw=1&pmid=25467802 #FOAvip Complement, part of the innate immune system, is involved with immune protection against invading pathogens as well as cell survival and tissue regeneration. It is known that complement activation is required for timely hepatocyte recovery following an acute toxic injury, but which pathway of complement activation is involved in response to hepatocyte injury has not been identified. In these studies we utilize mice deficient in C1qa, C4 and Factor D, lacking the classical, classical/MBL, and alternative pathways of complement activation, respectively, to identify an essential role for Factor D in the ability of the liver to recover from acute toxic injury. Here we demonstrate that following an acute CCl4-induced injury, the involvement of the alternative complement pathway is essential for efficient liver recovery. Twit Text FOAVip Alternative complement pathway component Factor D contributes to efficient clearance of tissue debris following acute CCl -induced injury ????Mol Immunol http://www.kidney.de/pget.php?&tw=1&pmid=25467802 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25467802 #FOAvip English Wikipedia <ref>{{Cite pmid|25467802 }}</ref> Alternative complement pathway component Factor D contributes to efficient clearance of tissue debris following acute CCl?-induced injury #MMPMID25467802 Cresci GA ; Allende D ; McMullen MR ; Nagy LE Mol Immunol 2015[Mar]; 64 (1 ): 9-17 PMID25467802 show ga Complement, part of the innate immune system, is involved with immune protection against invading pathogens as well as cell survival and tissue regeneration. It is known that complement activation is required for timely hepatocyte recovery following an acute toxic injury, but which pathway of complement activation is involved in response to hepatocyte injury has not been identified. In these studies we utilize mice deficient in C1qa, C4 and Factor D, lacking the classical, classical/MBL, and alternative pathways of complement activation, respectively, to identify an essential role for Factor D in the ability of the liver to recover from acute toxic injury. Here we demonstrate that following an acute CCl4-induced injury, the involvement of the alternative complement pathway is essential for efficient liver recovery. |Animals [MESH] |Carbon Tetrachloride [MESH] |Cell Proliferation [MESH] |Chemical and Drug Induced Liver Injury/*immunology/*pathology [MESH] |Complement C1q/deficiency [MESH] |Complement C3/metabolism [MESH] |Complement Factor D/deficiency/*metabolism [MESH] |Complement Pathway, Alternative/*immunology [MESH] |Female [MESH] |Hepatocytes/pathology [MESH] |Inflammation/pathology [MESH] |Interleukin-6/metabolism [MESH] |Liver/*immunology/*pathology [MESH] |Mice, Inbred C57BL [MESH] |Necrosis [MESH] |Neutrophil Infiltration [MESH] |Phosphorylation [MESH]Alternative complement pathway component Factor D contributes to effic(epmc).pdf DeepDyve Pubget Overpricing