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10.1101/gad.246173.114 http://scihub22266oqcxt.onion/10.1101/gad.246173.114 C4281563!4281563!25561494     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genes+Dev 2015 ; 29 (1): 39-47 Nephropedia Template TP {{tp|p=25561494|t=2015. Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolide |pdf=|usr=}}{{25561494}} gab.com Text Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolide JO: Genes Dev http://www.kidney.de/pget.php?&tw=1&pmid=25561494 #FOAvip Genome-wide studies have demonstrated that the phenomenon of promoter-bound Pol II pausing is widespread, especially for genes involved in developmental and stimulus-responsive pathways. Here, Chen et al. used the small molecule triptolide (TPL), an XPB/TFIIH inhibitor, to block transcriptional initiation and then measured Pol II occupancy by ChIP-seq. This revealed that most genes with paused Pol II show significant clearance of Pol II during the period of TPL treatment. They also identified a group of genes with unexpectedly stably paused Pol II, with unchanged Pol II occupancy during 1 h of inhibition of initiation. Twit Text FOAVip Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolide ????Genes Dev http://www.kidney.de/pget.php?&tw=1&pmid=25561494 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25561494 #FOAvip English Wikipedia <ref>{{Cite pmid|25561494}}</ref> Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolide #MMPMID25561494 Chen F; Gao X; Shilatifard A Genes Dev 2015[Jan]; 29 (1): 39-47 PMID25561494show ga Genome-wide studies have demonstrated that the phenomenon of promoter-bound Pol II pausing is widespread, especially for genes involved in developmental and stimulus-responsive pathways. Here, Chen et al. used the small molecule triptolide (TPL), an XPB/TFIIH inhibitor, to block transcriptional initiation and then measured Pol II occupancy by ChIP-seq. This revealed that most genes with paused Pol II show significant clearance of Pol II during the period of TPL treatment. They also identified a group of genes with unexpectedly stably paused Pol II, with unchanged Pol II occupancy during 1 h of inhibition of initiation. äStably paused genes revealed through inhibition of transcription initi(epmc).pdf DeepDyve Pubget Overpricing