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10.1038/nri3707 http://scihub22266oqcxt.onion/10.1038/nri3707 C4281037!4281037!25145755     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Rev+Immunol 2014 ; 14 (9): 585-600 Nephropedia Template TP {{tp|p=25145755|t=2014. IL-23-IL-17 immune axis: Discovery, Mechanistic Understanding, and Clinical Testing |pdf=|usr=}}{{25145755}} gab.com Text IL-23-IL-17 immune axis: Discovery, Mechanistic Understanding, and Clinical Testing JO: Nat Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=25145755 #FOAvip With the discovery of Th17 cells, the past decade has witnessed a major revision of the T helper subset paradigm and significant progress has been made deciphering the molecular mechanisms for T cell lineage commitment and function. In this review, we focus on the recent advances on the transcriptional control of Th17 cell plasticity and stability as well as the effector functions of Th17 cells?highlighting IL-17 signaling mechanisms in mesenchymal and barrier epithelial tissues. We also discuss the emerging clinical data showing anti-IL-17 and anti-IL-23 treatments are remarkably effective for many immune-mediated inflammatory diseases. Twit Text FOAVip IL-23-IL-17 immune axis: Discovery, Mechanistic Understanding, and Clinical Testing ????Nat Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=25145755 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25145755 #FOAvip English Wikipedia <ref>{{Cite pmid|25145755}}</ref> IL-23-IL-17 immune axis: Discovery, Mechanistic Understanding, and Clinical Testing #MMPMID25145755 Gaffen SL; Jain R; Garg AV; Cua DJ Nat Rev Immunol 2014[Sep]; 14 (9): 585-600 PMID25145755show ga With the discovery of Th17 cells, the past decade has witnessed a major revision of the T helper subset paradigm and significant progress has been made deciphering the molecular mechanisms for T cell lineage commitment and function. In this review, we focus on the recent advances on the transcriptional control of Th17 cell plasticity and stability as well as the effector functions of Th17 cells?highlighting IL-17 signaling mechanisms in mesenchymal and barrier epithelial tissues. We also discuss the emerging clinical data showing anti-IL-17 and anti-IL-23 treatments are remarkably effective for many immune-mediated inflammatory diseases. äIL-23-IL-17 immune axis: Discovery, Mechanistic Understanding, and Cli(epmc).pdf DeepDyve Pubget Overpricing