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10.1016/j.beha.2014.10.014 http://scihub22266oqcxt.onion/10.1016/j.beha.2014.10.014 C4277205!4277205!25455270     free     free     free       Best+Pract+Res+Clin+Haematol 2014 ; 27 (ä): 222-8 Nephropedia Template TP {{tp|p=25455270|t=2014. Advances in T-cell therapy for ALL |pdf=|usr=}}{{25455270}} gab.com Text Advances in T-cell therapy for ALL JO: Best Pract Res Clin Haematol http://www.kidney.de/pget.php?&tw=1&pmid=25455270 #FOAvip CD19-directed chimeric antigen receptor T cells (CART19 or CTL019) have been used with success in pediatric and adult acute lymphocytic leukemia (ALL) and chronic lymphocytic leukemia (CLL) patients. While this therapy has caused toxicities, including cytokine release syndrome and macrophage activation syndrome, these conditions are reversible with IL-6 blockade using the monoclonal antibody tocilizumab. Furthermore, 90% of the very high-risk patients who underwent infusion with CTL019 achieved a complete response, despite the fact that they previously failed multiple therapies and/or transplant. With improved cell persistence, this immunotherapy may one day prove to be more than a bridge to transplant and may in fact be a transplant alternative. Twit Text FOAVip Advances in T-cell therapy for ALL ????Best Pract Res Clin Haematol http://www.kidney.de/pget.php?&tw=1&pmid=25455270 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25455270 #FOAvip English Wikipedia <ref>{{Cite pmid|25455270}}</ref> Advances in T-cell therapy for ALL #MMPMID25455270 Grupp SA Best Pract Res Clin Haematol 2014[Sep]; 27 (ä): 222-8 PMID25455270show ga CD19-directed chimeric antigen receptor T cells (CART19 or CTL019) have been used with success in pediatric and adult acute lymphocytic leukemia (ALL) and chronic lymphocytic leukemia (CLL) patients. While this therapy has caused toxicities, including cytokine release syndrome and macrophage activation syndrome, these conditions are reversible with IL-6 blockade using the monoclonal antibody tocilizumab. Furthermore, 90% of the very high-risk patients who underwent infusion with CTL019 achieved a complete response, despite the fact that they previously failed multiple therapies and/or transplant. With improved cell persistence, this immunotherapy may one day prove to be more than a bridge to transplant and may in fact be a transplant alternative. äAdvances in T-cell therapy for ALL (epmc).pdf DeepDyve Pubget Overpricing