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10.1074/jbc.M114.592097 http://scihub22266oqcxt.onion/10.1074/jbc.M114.592097 C4276864!4276864!25389294     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biol+Chem 2014 ; 289 (52): 35969-78 Nephropedia Template TP {{tp|p=25389294|t=2014. Structural and Biochemical Insights into the Activation Mechanisms of Germinal Center Kinase OSR1* |pdf=|usr=}}{{25389294}} gab.com Text Structural and Biochemical Insights into the Activation Mechanisms of Germinal Center Kinase OSR1* JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=25389294 #FOAvip Background: OSR1 modulates ion homeostasis and cell volume in mammal.Results: The CCT domain and ?AL helix of OSR1 act together to suppress its basal activity, while WNKs and MO25 unlock such autoinhibition for full activation.Conclusion: OSR1 activity is regulated by autoinhibition, WNKs, and MO25.Significance: This work provides insights into the regulatory mechanisms of OSR1 activation to facilitate functional study. Twit Text FOAVip Structural and Biochemical Insights into the Activation Mechanisms of Germinal Center Kinase OSR1* ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=25389294 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25389294 #FOAvip English Wikipedia <ref>{{Cite pmid|25389294}}</ref> Structural and Biochemical Insights into the Activation Mechanisms of Germinal Center Kinase OSR1* #MMPMID25389294 Li C; Feng M; Shi Z; Hao Q; Song X; Wang W; Zhao Y; Jiao S; Zhou Z J Biol Chem 2014[Dec]; 289 (52): 35969-78 PMID25389294show ga Background: OSR1 modulates ion homeostasis and cell volume in mammal.Results: The CCT domain and ?AL helix of OSR1 act together to suppress its basal activity, while WNKs and MO25 unlock such autoinhibition for full activation.Conclusion: OSR1 activity is regulated by autoinhibition, WNKs, and MO25.Significance: This work provides insights into the regulatory mechanisms of OSR1 activation to facilitate functional study. äStructural and Biochemical Insights into the Activation Mechanisms of (epmc).pdf DeepDyve Pubget Overpricing