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10.1002/adma.201304891

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suck abstract from ncbi


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pmid25205057
      Adv+Mater 2014 ; 26 (46 ): 7849-72
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  • Applications of synchrotron-based spectroscopic techniques in studying nucleic acids and nucleic acid-functionalized nanomaterials #MMPMID25205057
  • Wu P ; Yu Y ; McGhee CE ; Tan LH ; Lu Y
  • Adv Mater 2014[Dec]; 26 (46 ): 7849-72 PMID25205057 show ga
  • In this review, we summarize recent progress in the application of synchrotron-based spectroscopic techniques for nucleic acid research that takes advantage of high-flux and high-brilliance electromagnetic radiation from synchrotron sources. The first section of the review focuses on the characterization of the structure and folding processes of nucleic acids using different types of synchrotron-based spectroscopies, such as X-ray absorption spectroscopy, X-ray emission spectroscopy, X-ray photoelectron spectroscopy, synchrotron radiation circular dichroism, X-ray footprinting and small-angle X-ray scattering. In the second section, the characterization of nucleic acid-based nanostructures, nucleic acid-functionalized nanomaterials and nucleic acid-lipid interactions using these spectroscopic techniques is summarized. Insights gained from these studies are described and future directions of this field are also discussed.
  • |*Synchrotrons [MESH]
  • |Circular Dichroism [MESH]
  • |Nanostructures/*chemistry [MESH]
  • |Nucleic Acid Conformation [MESH]
  • |Nucleic Acids/*chemistry [MESH]
  • |Photoelectron Spectroscopy [MESH]
  • |Scattering, Small Angle [MESH]
  • |Spectrometry, X-Ray Emission [MESH]
  • |X-Ray Absorption Spectroscopy [MESH]


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