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2014 ; 14
(7
): 1630-7
Nephropedia Template TP
gab.com Text
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English Wikipedia
A randomized, prospective, parallel group study of laparoscopic versus
laparoendoscopic single site donor nephrectomy for kidney donation
#MMPMID24934732
Aull MJ
; Afaneh C
; Charlton M
; Serur D
; Douglas M
; Christos PJ
; Kapur S
; Del Pizzo JJ
Am J Transplant
2014[Jul]; 14
(7
): 1630-7
PMID24934732
show ga
Few prospective, randomized studies have assessed the benefits of
laparoendoscopic single site donor nephrectomy (LESS-DN) over laparoscopic donor
nephrectomy (LDN). Our center initiated such a trial in January 2011, following
subjects randomized to LESS-DN versus LDN from surgery through 5 years
postdonation. Subjects complete recovery/satisfaction questionnaires at 2, 6 and
12 months postdonation; transplant recipient outcomes are also recorded. One
hundred subjects (49 LESS-DN, 51 LDN) underwent surgery; donor demographics were
similar between groups, and included a predominance of female, living-unrelated
donors, mean age of 47 years who underwent left donor nephrectomy. Operative
parameters (overall time, time to extraction, warm ischemia time, blood loss)
were similar between groups. Conversion to hand-assist laparoscopy was required
in 3 LESS-DN (6.1%) versus 2 LDN (3.9%; p?=?0.67). Questionnaires revealed that
97.2% of LESS-DN versus 79.5% of LDN (p?=?0.03) were 100% recovered by 2 months
after donation. No significant difference was seen in satisfaction scores between
the groups. Recipient outcomes were similar between groups. Our randomized trial
comparing LESS donor nephrectomy to LDN confirms that LESS-DN offers a safe
alternative to conventional LDN in terms of intra- and post-operative
complications. LDN and LESS-DN offer similar recovery and satisfaction after
donation.
|*Kidney Transplantation
[MESH]
|*Living Donors
[MESH]
|Endoscopy/*methods
[MESH]
|Female
[MESH]
|Follow-Up Studies
[MESH]
|Glomerular Filtration Rate
[MESH]
|Humans
[MESH]
|Kidney Function Tests
[MESH]
|Laparoscopy/*methods
[MESH]
|Length of Stay/statistics & numerical data
[MESH]