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10.1073/pnas.1418796111 http://scihub22266oqcxt.onion/10.1073/pnas.1418796111 C4273342!4273342!25468969     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2014 ; 111 (50): 17715-22 Nephropedia Template TP {{tp|p=25468969|t=2014. Microtubule nucleation remote from centrosomes may explain how asters span large cells |pdf=|usr=}}{{25468969}} gab.com Text Microtubule nucleation remote from centrosomes may explain how asters span large cells JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25468969 #FOAvip How the cell cytoplasm is spatially organized is of fundamental interest. In ordinary animal cells the cytoplasm is organized by a radial array of microtubules, called an aster. Aster microtubules are nucleated by the centrosome and elongate to the periphery. We investigated how asters grow in an extremely large cell, the frog egg, using microscopy of an extract system. Asters were initially nucleated at centrosomes, but then additional microtubules nucleated far from the centrosome, apparently stimulated by preexisting microtubules. The resulting growth process allows asters to scale to the size of huge egg cells while maintaining a high density of microtubules at the periphery. Microtubule-stimulated microtubule nucleation might be a general principle for organizing large cells. Twit Text FOAVip Microtubule nucleation remote from centrosomes may explain how asters span large cells ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25468969 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25468969 #FOAvip English Wikipedia <ref>{{Cite pmid|25468969}}</ref> Microtubule nucleation remote from centrosomes may explain how asters span large cells #MMPMID25468969 Ishihara K; Nguyen PA; Groen AC; Field CM; Mitchison TJ Proc Natl Acad Sci U S A 2014[Dec]; 111 (50): 17715-22 PMID25468969show ga How the cell cytoplasm is spatially organized is of fundamental interest. In ordinary animal cells the cytoplasm is organized by a radial array of microtubules, called an aster. Aster microtubules are nucleated by the centrosome and elongate to the periphery. We investigated how asters grow in an extremely large cell, the frog egg, using microscopy of an extract system. Asters were initially nucleated at centrosomes, but then additional microtubules nucleated far from the centrosome, apparently stimulated by preexisting microtubules. The resulting growth process allows asters to scale to the size of huge egg cells while maintaining a high density of microtubules at the periphery. Microtubule-stimulated microtubule nucleation might be a general principle for organizing large cells. äMicrotubule nucleation remote from centrosomes may explain how asters (epmc).pdf DeepDyve Pubget Overpricing