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10.1073/pnas.1420096111

http://scihub22266oqcxt.onion/10.1073/pnas.1420096111
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C4273332!4273332!25453095
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suck abstract from ncbi


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pmid25453095      Proc+Natl+Acad+Sci+U+S+A 2014 ; 111 (50): 17827-32
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  • Direct interactions promote eviction of the Sir3 heterochromatin protein by the SWI/SNF chromatin remodeling enzyme #MMPMID25453095
  • Manning BJ; Peterson CL
  • Proc Natl Acad Sci U S A 2014[Dec]; 111 (50): 17827-32 PMID25453095show ga
  • Heterochromatin is a repressive mode of genetic storage that prevents cellular machineries from accessing DNA sequences. Here, we investigate how a protein machine, called SWI/SNF, can disrupt these heterochromatin structures and facilitate nuclear processes. We identify physical and functional interactions between SWI/SNF and a key heterochromatin protein, silent information regulator 3p (Sir3p).
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