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10.1074/jbc.M114.597740

http://scihub22266oqcxt.onion/10.1074/jbc.M114.597740
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C4271240!4271240!25378389
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suck abstract from ncbi


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pmid25378389      J+Biol+Chem 2014 ; 289 (51): 35570-81
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  • Nitroxyl (HNO) Reacts with Molecular Oxygen and Forms Peroxynitrite at Physiological pH: BIOLOGICAL IMPLICATIONS* #MMPMID25378389
  • Smulik R; D?bski D; Zielonka J; Micha?owski B; Adamus J; Marcinek A; Kalyanaraman B; Sikora A
  • J Biol Chem 2014[Dec]; 289 (51): 35570-81 PMID25378389show ga
  • Background: Nitroxyl (HNO) is a reactive nitrogen species implicated in cardioprotection.Results: Nitroxyl reacts with oxygen to form an oxidizing and nitrating species, peroxynitrite.Conclusion: In the presence of oxygen, HNO donors may be a source of peroxynitrite.Significance: Peroxynitrite formation should be taken into account in the extracellular milieu when exposing cells to HNO donor under aerobic conditions.
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