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10.1152/ajplung.00318.2014 http://scihub22266oqcxt.onion/10.1152/ajplung.00318.2014 C4269690!4269690!25381026     free     free     free       Am+J+Physiol+Lung+Cell+Mol+Physiol 2014 ; 307 (12): L924-35 Nephropedia Template TP {{tp|p=25381026|t=2014. Novel regulators of endothelial barrier function |pdf=|usr=}}{{25381026}} gab.com Text Novel regulators of endothelial barrier function JO: Am J Physiol Lung Cell Mol Physiol http://www.kidney.de/pget.php?&tw=1&pmid=25381026 #FOAvip Endothelial barrier function is an essential and tightly regulated process that ensures proper compartmentalization of the vascular and interstitial space, while allowing for the diffusive exchange of small molecules and the controlled trafficking of macromolecules and immune cells. Failure to control endothelial barrier integrity results in excessive leakage of fluid and proteins from the vasculature that can rapidly become fatal in scenarios such as sepsis or the acute respiratory distress syndrome. Here, we highlight recent advances in our understanding on the regulation of endothelial permeability, with a specific focus on the endothelial glycocalyx and endothelial scaffolds, regulatory intracellular signaling cascades, as well as triggers and mediators that either disrupt or enhance endothelial barrier integrity, and provide our perspective as to areas of seeming controversy and knowledge gaps, respectively. Twit Text FOAVip Novel regulators of endothelial barrier function ????Am J Physiol Lung Cell Mol Physiol http://www.kidney.de/pget.php?&tw=1&pmid=25381026 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25381026 #FOAvip English Wikipedia <ref>{{Cite pmid|25381026}}</ref> Novel regulators of endothelial barrier function #MMPMID25381026 Mehta D; Ravindran K; Kuebler WM Am J Physiol Lung Cell Mol Physiol 2014[Dec]; 307 (12): L924-35 PMID25381026show ga Endothelial barrier function is an essential and tightly regulated process that ensures proper compartmentalization of the vascular and interstitial space, while allowing for the diffusive exchange of small molecules and the controlled trafficking of macromolecules and immune cells. Failure to control endothelial barrier integrity results in excessive leakage of fluid and proteins from the vasculature that can rapidly become fatal in scenarios such as sepsis or the acute respiratory distress syndrome. Here, we highlight recent advances in our understanding on the regulation of endothelial permeability, with a specific focus on the endothelial glycocalyx and endothelial scaffolds, regulatory intracellular signaling cascades, as well as triggers and mediators that either disrupt or enhance endothelial barrier integrity, and provide our perspective as to areas of seeming controversy and knowledge gaps, respectively. äNovel regulators of endothelial barrier function (epmc).pdf DeepDyve Pubget Overpricing