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10.1101/gad.249730.114

http://scihub22266oqcxt.onion/10.1101/gad.249730.114
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C4265678!4265678!25512562
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suck abstract from ncbi


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pmid25512562      Genes+Dev 2014 ; 28 (24): 2750-63
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  • Histone acetyltransferase Enok regulates oocyte polarization by promoting expression of the actin nucleation factor spire #MMPMID25512562
  • Huang F; Paulson A; Dutta A; Venkatesh S; Smolle M; Abmayr SM; Workman JL
  • Genes Dev 2014[Dec]; 28 (24): 2750-63 PMID25512562show ga
  • Huang et al. demonstrate that the Drosophila KAT6 Enok acetylates histone H3 Lys 23 (H3K23). Mutants lacking functional Enok lost germline formation and abdominal segments in the embryo. Enok is localized to and acetylates H3K23 at the spire (spir) and maelstrom (mael) genes, and expression of spir in the germline can largely rescue the defective Osk localization in enok mutant ovaries.
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