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10.1101/gad.247528.114 http://scihub22266oqcxt.onion/10.1101/gad.247528.114 C4265675!4265675!25512559     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genes+Dev 2014 ; 28 (24): 2712-25 Nephropedia Template TP {{tp|p=25512559|t=2014. HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia |pdf=|usr=}}{{25512559}} gab.com Text HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia JO: Genes Dev http://www.kidney.de/pget.php?&tw=1&pmid=25512559 #FOAvip Histone chaperone HIRA deposits variant histone H3.3 and histone H4 into chromatin in a DNA replication-independent manner. Rai et al. show that nonproliferating senescent cells express and incorporate histone H3.3 and other canonical core histones into a dynamic chromatin landscape, and this depends on HIRA. In senescent cells, but not proliferating cells, promoters of active genes are exceptionally enriched in H4K16ac, and HIRA is required for retention of H4K16ac. HIRA is also required for retention of H4K16ac in vivo and suppression of oncogene-induced neoplasia. Twit Text FOAVip HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia ????Genes Dev http://www.kidney.de/pget.php?&tw=1&pmid=25512559 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25512559 #FOAvip English Wikipedia <ref>{{Cite pmid|25512559}}</ref> HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia #MMPMID25512559 Rai TS; Cole JJ; Nelson DM; Dikovskaya D; Faller WJ; Vizioli MG; Hewitt RN; Anannya O; McBryan T; Manoharan I; van Tuyn J; Morrice N; Pchelintsev NA; Ivanov A; Brock C; Drotar ME; Nixon C; Clark W; Sansom OJ; Anderson KI; King A; Blyth K; Adams PD Genes Dev 2014[Dec]; 28 (24): 2712-25 PMID25512559show ga Histone chaperone HIRA deposits variant histone H3.3 and histone H4 into chromatin in a DNA replication-independent manner. Rai et al. show that nonproliferating senescent cells express and incorporate histone H3.3 and other canonical core histones into a dynamic chromatin landscape, and this depends on HIRA. In senescent cells, but not proliferating cells, promoters of active genes are exceptionally enriched in H4K16ac, and HIRA is required for retention of H4K16ac. HIRA is also required for retention of H4K16ac in vivo and suppression of oncogene-induced neoplasia. äHIRA orchestrates a dynamic chromatin landscape in senescence and is r(epmc).pdf DeepDyve Pubget Overpricing