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10.1016/j.cjca.2014.07.748 http://scihub22266oqcxt.onion/10.1016/j.cjca.2014.07.748 C4265566!4265566!25475464     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25475464&cmd=llinks): Failed to open stream: HTTP request failed! 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Appropriate Revascularization in Stable Angina, Lessons from the BARI 2D Trial |pdf=|usr=}}{{25475464}} gab.com Text Appropriate Revascularization in Stable Angina, Lessons from the BARI 2D Trial JO: Can J Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=25475464 #FOAvip Background: The 2012 Guidelines for Diagnosis and Management of Patients with Stable Ischemic Heart Disease recommend intensive antianginal and risk factor treatment (OMT) before considering revascularization to relieve symptoms. The Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) randomized patients with ischemic heart disease and anatomy suitable to revascularization to 1): initial OMT with revascularization if needed or 2): initial revascularization plus OMT, and found no difference in major cardiovascular events. Ultimately, however, 37.9% of the OMT group was revascularized (crossed over) during the 5 year follow-up period. METHODS: Data from the 1192 patients randomized to OMT were analyzed to identify subgroups where the incidence of revascularization was so high that direct revascularization without a trial period could be justified. Multivariate logistic, Cox regression models of baseline data and a landmark analysis of participants not revascularized at six months were constructed. RESULTS: The models using only data available at the time of study entry had limited predictive value for revascularization by 6 months or by 5 years; however, the model incorporating severity of angina during the first 6 months could better predict revascularization (C statistic = .789). CONCLUSIONS: With the possible exception of patients with severe angina and proximal LAD disease, this analysis supports the recommendation of the 2012 GUIDELINES for a trial of OMT prior to revascularization. Patients could NOT be identified at the time of catheterization, but a short period of close follow-up during OMT identified the nearly 40% of patients who underwent revascularization. Twit Text FOAVip Appropriate Revascularization in Stable Angina, Lessons from the BARI 2D Trial ????Can J Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=25475464 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25475464 #FOAvip English Wikipedia <ref>{{Cite pmid|25475464}}</ref> Appropriate Revascularization in Stable Angina, Lessons from the BARI 2D Trial #MMPMID25475464 Krone RJ; Althouse AD; Tamis-Holland J; Venkitachalam L; Campos A; Forker A; Jacobs AK; Ocampo S; Steiner G; Fuentes F; Sing IRP; Brooks MM Can J Cardiol 2014[Dec]; 30 (12): 1595-601 PMID25475464show ga Background: The 2012 Guidelines for Diagnosis and Management of Patients with Stable Ischemic Heart Disease recommend intensive antianginal and risk factor treatment (OMT) before considering revascularization to relieve symptoms. The Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) randomized patients with ischemic heart disease and anatomy suitable to revascularization to 1): initial OMT with revascularization if needed or 2): initial revascularization plus OMT, and found no difference in major cardiovascular events. Ultimately, however, 37.9% of the OMT group was revascularized (crossed over) during the 5 year follow-up period. METHODS: Data from the 1192 patients randomized to OMT were analyzed to identify subgroups where the incidence of revascularization was so high that direct revascularization without a trial period could be justified. Multivariate logistic, Cox regression models of baseline data and a landmark analysis of participants not revascularized at six months were constructed. RESULTS: The models using only data available at the time of study entry had limited predictive value for revascularization by 6 months or by 5 years; however, the model incorporating severity of angina during the first 6 months could better predict revascularization (C statistic = .789). CONCLUSIONS: With the possible exception of patients with severe angina and proximal LAD disease, this analysis supports the recommendation of the 2012 GUIDELINES for a trial of OMT prior to revascularization. Patients could NOT be identified at the time of catheterization, but a short period of close follow-up during OMT identified the nearly 40% of patients who underwent revascularization. äAppropriate Revascularization in Stable Angina, Lessons from the BARI (epmc).pdf DeepDyve Pubget Overpricing