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10.1074/jbc.R114.609776

http://scihub22266oqcxt.onion/10.1074/jbc.R114.609776
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C4263848!4263848!25336646
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suck abstract from ncbi


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pmid25336646      J+Biol+Chem 2014 ; 289 (50): 34422-3
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  • Minireview Series on the Thirtieth Anniversary of Research on O-GlcNAcylation of Nuclear and Cytoplasmic Proteins: Nutrient Regulation of Cellular Metabolism and Physiology by O-GlcNAcylation #MMPMID25336646
  • Hart GW
  • J Biol Chem 2014[Dec]; 289 (50): 34422-3 PMID25336646show ga
  • The dynamic cycling of N-acetylglucosamine (termed O-GlcNAcylation) on serine or threonine residues of nuclear or cytoplasmic proteins serves as a nutrient sensor, both independently and also via its interplay with other post-translational modifications, to regulate signaling, transcription, and cellular physiology. Emerging evidence suggests that dysregulation of this ubiquitous post-translational modification contributes to the etiology of some the most important human chronic diseases.
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