Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1073/pnas.1415663111 http://scihub22266oqcxt.onion/10.1073/pnas.1415663111 C4260602!4260602!25404291     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2014 ; 111 (48): 17158-63 Nephropedia Template TP {{tp|p=25404291|t=2014. Orientation of aromatic residues in amyloid cores: Structural insights into prion fiber diversity |pdf=|usr=}}{{25404291}} gab.com Text Orientation of aromatic residues in amyloid cores: Structural insights into prion fiber diversity JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25404291 #FOAvip Amyloids, which are protein fiber aggregates, are often associated with neurodegenerative diseases such as Alzheimer?s, but they can also be beneficial, as in yeasts, where they help cells adapt to environmental changes. Intriguingly, the same protein has the ability to aggregate into different fiber forms, known as strains, that generate distinct biological phenotypes. Structurally, little is known about strains. Using polarized light spectroscopy, we provide structural information on two distinct phenotypic strains of the yeast translation termination factor, Sup35. Remarkably, they show similar orientation of aromatic residues in the fiber core relative to the fiber direction, suggesting similar structures. Small variations are observed, indicating different local environments for aromatic residues outside the core, reflecting differences in fiber packing. Twit Text FOAVip Orientation of aromatic residues in amyloid cores: Structural insights into prion fiber diversity ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25404291 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25404291 #FOAvip English Wikipedia <ref>{{Cite pmid|25404291}}</ref> Orientation of aromatic residues in amyloid cores: Structural insights into prion fiber diversity #MMPMID25404291 Reymer A; Frederick KK; Rocha S; Beke-Somfai T; Kitts CC; Lindquist S; Nordén B Proc Natl Acad Sci U S A 2014[Dec]; 111 (48): 17158-63 PMID25404291show ga Amyloids, which are protein fiber aggregates, are often associated with neurodegenerative diseases such as Alzheimer?s, but they can also be beneficial, as in yeasts, where they help cells adapt to environmental changes. Intriguingly, the same protein has the ability to aggregate into different fiber forms, known as strains, that generate distinct biological phenotypes. Structurally, little is known about strains. Using polarized light spectroscopy, we provide structural information on two distinct phenotypic strains of the yeast translation termination factor, Sup35. Remarkably, they show similar orientation of aromatic residues in the fiber core relative to the fiber direction, suggesting similar structures. Small variations are observed, indicating different local environments for aromatic residues outside the core, reflecting differences in fiber packing. äOrientation of aromatic residues in amyloid cores: Structural insights(epmc).pdf DeepDyve Pubget Overpricing