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10.1073/pnas.1412663111 http://scihub22266oqcxt.onion/10.1073/pnas.1412663111 C4260590!4260590!25404305     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25404305&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 500 Internal Server Error in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2014 ; 111 (48): E5169-77 Nephropedia Template TP {{tp|p=25404305|t=2014. Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion |pdf=|usr=}}{{25404305}} gab.com Text Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25404305 #FOAvip Gastrointestinal worms (helminths) infect more than 2 billion people, and vaccines are not yet available. Helminths elicit a type 2 immune response characterized by high serum IgE levels and increased numbers of IL-4? or IL-13?secreting effector cells including Th2 cells, eosinophils, basophils, and type 2 innate lymphoid cells. We determined the mechanism by which basophils contribute to protection against secondary infections with gastrointestinal helminths. Here we demonstrate that basophils are recruited into the small intestine of infected mice and orchestrate the local type 2 immune response in this tissue. Basophil-mediated protection required the presence of IgE and the expression of activating Fc receptors and IL-4/IL-13 in basophils. These findings could help the development of new vaccination strategies against helminths. Twit Text FOAVip Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25404305 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25404305 #FOAvip English Wikipedia <ref>{{Cite pmid|25404305}}</ref> Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion #MMPMID25404305 Schwartz C; Turqueti-Neves A; Hartmann S; Yu P; Nimmerjahn F; Voehringer D Proc Natl Acad Sci U S A 2014[Dec]; 111 (48): E5169-77 PMID25404305show ga Gastrointestinal worms (helminths) infect more than 2 billion people, and vaccines are not yet available. Helminths elicit a type 2 immune response characterized by high serum IgE levels and increased numbers of IL-4? or IL-13?secreting effector cells including Th2 cells, eosinophils, basophils, and type 2 innate lymphoid cells. We determined the mechanism by which basophils contribute to protection against secondary infections with gastrointestinal helminths. Here we demonstrate that basophils are recruited into the small intestine of infected mice and orchestrate the local type 2 immune response in this tissue. Basophil-mediated protection required the presence of IgE and the expression of activating Fc receptors and IL-4/IL-13 in basophils. These findings could help the development of new vaccination strategies against helminths. äBasophil-mediated protection against gastrointestinal helminths requir(epmc).pdf DeepDyve Pubget Overpricing