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10.1073/pnas.1413725111 http://scihub22266oqcxt.onion/10.1073/pnas.1413725111 C4260558!4260558!25404299     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2014 ; 111 (48): 17308-13 Nephropedia Template TP {{tp|p=25404299|t=2014. Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling |pdf=|usr=}}{{25404299}} gab.com Text Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25404299 #FOAvip Atherosclerosis, the major cause of death and illness in industrialized nations, develops in regions of arteries in which fluid flow patterns are disturbed and endothelial cells fail to align in the direction of flow. In contrast, regions of laminar flow in which cells are aligned are protected. The current work shows that the transmembrane proteoglycan syndecan 4 is required for endothelial cell alignment in the direction of flow and for the protective effect of high laminar flow, yet other flow responses are intact. The data therefore identify a role for syndecan 4 in flow direction sensing, show that sensing flow direction is separable from sensing flow magnitude, and provide new support for the key role of cell alignment in atheroprotection. Twit Text FOAVip Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25404299 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25404299 #FOAvip English Wikipedia <ref>{{Cite pmid|25404299}}</ref> Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling #MMPMID25404299 Baeyens N; Mulligan-Kehoe MJ; Corti F; Simon DD; Ross TD; Rhodes JM; Wang TZ; Mejean CO; Simons M; Humphrey J; Schwartz MA Proc Natl Acad Sci U S A 2014[Dec]; 111 (48): 17308-13 PMID25404299show ga Atherosclerosis, the major cause of death and illness in industrialized nations, develops in regions of arteries in which fluid flow patterns are disturbed and endothelial cells fail to align in the direction of flow. In contrast, regions of laminar flow in which cells are aligned are protected. The current work shows that the transmembrane proteoglycan syndecan 4 is required for endothelial cell alignment in the direction of flow and for the protective effect of high laminar flow, yet other flow responses are intact. The data therefore identify a role for syndecan 4 in flow direction sensing, show that sensing flow direction is separable from sensing flow magnitude, and provide new support for the key role of cell alignment in atheroprotection. äSyndecan 4 is required for endothelial alignment in flow and atheropro(epmc).pdf DeepDyve Pubget Overpricing