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10.1016/j.tim.2014.09.001 http://scihub22266oqcxt.onion/10.1016/j.tim.2014.09.001 C4256103!4256103!25262420     free     free     free       Trends+Microbiol 2014 ; 22 (12): 707-14 Nephropedia Template TP {{tp|p=25262420|t=2014. Candida albicans hyphal initiation and elongation |pdf=|usr=}}{{25262420}} gab.com Text Candida albicans hyphal initiation and elongation JO: Trends Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=25262420 #FOAvip The fungus Candida albicans is a benign member of the mucosal microbiota, but can cause mucosal infections and life-threatening disseminated invasive infections in susceptible individuals. The ability to switch between yeast, pseudohyphal, and hyphal growth forms (polymorphism) is one of the most investigated virulence attributes of C. albicans. Recent studies suggest that hyphal development in C. albicans requires two temporally linked regulations for initiation and maintenance of the hyphal transcriptional program. Hyphal initiation requires a rapid but temporary disappearance of the Nrg1 transcriptional repressor of hyphal morphogenesis. Hyphal maintenance requires active sensing of the surrounding environment, leading to exclusion of Nrg1 binding to promoters of hypha-specific genes or reduced NRG1 expression. We discuss recent advances in understanding the complex transcriptional regulation of hyphal gene expression. These provide molecular mechanisms underpinning phenotypic plasticity of C. albicans polymorphism. Twit Text FOAVip Candida albicans hyphal initiation and elongation ????Trends Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=25262420 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25262420 #FOAvip English Wikipedia <ref>{{Cite pmid|25262420}}</ref> Candida albicans hyphal initiation and elongation #MMPMID25262420 Lu Y; Su C; Liu H Trends Microbiol 2014[Dec]; 22 (12): 707-14 PMID25262420show ga The fungus Candida albicans is a benign member of the mucosal microbiota, but can cause mucosal infections and life-threatening disseminated invasive infections in susceptible individuals. The ability to switch between yeast, pseudohyphal, and hyphal growth forms (polymorphism) is one of the most investigated virulence attributes of C. albicans. Recent studies suggest that hyphal development in C. albicans requires two temporally linked regulations for initiation and maintenance of the hyphal transcriptional program. Hyphal initiation requires a rapid but temporary disappearance of the Nrg1 transcriptional repressor of hyphal morphogenesis. Hyphal maintenance requires active sensing of the surrounding environment, leading to exclusion of Nrg1 binding to promoters of hypha-specific genes or reduced NRG1 expression. We discuss recent advances in understanding the complex transcriptional regulation of hyphal gene expression. These provide molecular mechanisms underpinning phenotypic plasticity of C. albicans polymorphism. äCandida albicans hyphal initiation and elongation (epmc).pdf DeepDyve Pubget Overpricing