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10.1016/j.bpj.2014.10.045 http://scihub22266oqcxt.onion/10.1016/j.bpj.2014.10.045 C4255218!4255218!25468344     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biophys+J 2014 ; 107 (11): 2652-61 Nephropedia Template TP {{tp|p=25468344|t=2014. Self-Organizing Actomyosin Patterns on the Cell Cortex at Epithelial Cell-Cell Junctions |pdf=|usr=}}{{25468344}} gab.com Text Self-Organizing Actomyosin Patterns on the Cell Cortex at Epithelial Cell-Cell Junctions JO: Biophys J http://www.kidney.de/pget.php?&tw=1&pmid=25468344 #FOAvip The behavior of actomyosin critically determines morphologically distinct patterns of contractility found at the interface between adherent cells. One such pattern is found at the apical region (zonula adherens) of cell-cell junctions in epithelia, where clusters of the adhesion molecule E-cadherin concentrate in a static pattern. Meanwhile, E-cadherin clusters throughout lateral cell-cell contacts display dynamic movements in the plane of the junctions. To gain insight into the principles that determine the nature and organization of these dynamic structures, we analyze this behavior by modeling the 2D actomyosin cell cortex as an active fluid medium. The numerical simulations show that the stability of the actin filaments influences the spatial structure and dynamics of the system. We find that in addition to static Turing-type patterns, persistent dynamic behavior occurs in a wide range of parameters. In the 2D model, mechanical stress-dependent actin breakdown is shown to produce a continuously changing network of actin bridges, whereas with a constant breakdown rate, more isolated clusters of actomyosin tend to form. The model qualitatively reproduces the dynamic and stable patterns experimentally observed at the junctions between epithelial cells. Twit Text FOAVip Self-Organizing Actomyosin Patterns on the Cell Cortex at Epithelial Cell-Cell Junctions ????Biophys J http://www.kidney.de/pget.php?&tw=1&pmid=25468344 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25468344 #FOAvip English Wikipedia <ref>{{Cite pmid|25468344}}</ref> Self-Organizing Actomyosin Patterns on the Cell Cortex at Epithelial Cell-Cell Junctions #MMPMID25468344 Moore T; Wu S; Michael M; Yap A; Gomez G; Neufeld Z Biophys J 2014[Dec]; 107 (11): 2652-61 PMID25468344show ga The behavior of actomyosin critically determines morphologically distinct patterns of contractility found at the interface between adherent cells. One such pattern is found at the apical region (zonula adherens) of cell-cell junctions in epithelia, where clusters of the adhesion molecule E-cadherin concentrate in a static pattern. Meanwhile, E-cadherin clusters throughout lateral cell-cell contacts display dynamic movements in the plane of the junctions. To gain insight into the principles that determine the nature and organization of these dynamic structures, we analyze this behavior by modeling the 2D actomyosin cell cortex as an active fluid medium. The numerical simulations show that the stability of the actin filaments influences the spatial structure and dynamics of the system. We find that in addition to static Turing-type patterns, persistent dynamic behavior occurs in a wide range of parameters. In the 2D model, mechanical stress-dependent actin breakdown is shown to produce a continuously changing network of actin bridges, whereas with a constant breakdown rate, more isolated clusters of actomyosin tend to form. The model qualitatively reproduces the dynamic and stable patterns experimentally observed at the junctions between epithelial cells. äSelf-Organizing Actomyosin Patterns on the Cell Cortex at Epithelial C(epmc).pdf DeepDyve Pubget Overpricing