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Studying brain organization via spontaneous fMRI signal #MMPMID25459408
Power JD; Schlaggar BL; Petersen SE
Neuron 2014[Nov]; 84 (4): 681-96 PMID25459408show ga
In recent years, some substantial advances in understanding human (and non-human) brain organization have emerged from a relatively unusual approach: the observation of spontaneous activity, and correlated patterns in spontaneous activity, in the ?resting? brain. Most commonly, spontaneous neural activity is measured indirectly via fMRI signal in subjects who are lying quietly in the scanner, the so-called ?resting state?. This Primer introduces the fMRI-based study of spontaneous brain activity, some of the methodological issues active in the field, and some ways in which resting state fMRI has been used to delineate aspects of area-level and supra-areal brain organization.