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10.1016/j.coi.2014.08.005

http://scihub22266oqcxt.onion/10.1016/j.coi.2014.08.005
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C4254370!4254370!25216261
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suck abstract from ncbi


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pmid25216261      Curr+Opin+Immunol 2014 ; ä (ä): 24-30
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  • Molecular Mechanisms for Contribution of MHC Molecules to Autoimmune Diseases #MMPMID25216261
  • Sollid LM; Pos W; Wucherpfennig KW
  • Curr Opin Immunol 2014[Dec]; ä (ä): 24-30 PMID25216261show ga
  • It will soon be 50 years since the first MHC associations with human disease were described. These seminal studies opened a flourishing area of research, yet much remains to be discovered. Genome-wide association studies of autoimmune diseases have demonstrated that the MHC region has effect sizes that supersede those for any non-MHC locus for most diseases. Thus, an understanding of how particular MHC alleles confer susceptibility will be essential for a comprehensive understanding of autoimmune disease pathogenesis. Here we review recent exciting findings in this important field.
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