Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.semcdb.2014.08.011 http://scihub22266oqcxt.onion/10.1016/j.semcdb.2014.08.011 C4254347!4254347!25171873     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Semin+Cell+Dev+Biol 2014 ; ä (ä): 157-65 Nephropedia Template TP {{tp|p=25171873|t=2014. Architecture of tight junctions and principles of molecular composition |pdf=|usr=}}{{25171873}} gab.com Text Architecture of tight junctions and principles of molecular composition JO: Semin Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=25171873 #FOAvip The tight junction creates an intercellular barrier limiting paracellular movement of solutes and material across epithelia. Currently many proteins have been identified as components of the tight junction and understanding their architectural organization and interactions is critical to understanding the biology of the barrier. In general the architecture can be conceptualized into compartments with the transmembrane barrier proteins (claudins, occludin, JAM-A, etc.), linked to peripheral scaffolding proteins (such as ZO-1, afadin, MAGI1, etc.) which are in turned linked to actin and microtubules through numerous linkers (cingulin, myosins, protein 4.1, etc.). Within this complex network are associated many signaling proteins that affect the barrier and broader cell functions. The PDZ domain is a commonly used motif to specifically link individual junction protein pairs. Here we review some of the key proteins defining the tight junction and general themes of their organization with the perspective that much will be learned about function by characterizing the detailed architecture and subcompartments within the junction. Twit Text FOAVip Architecture of tight junctions and principles of molecular composition ????Semin Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=25171873 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25171873 #FOAvip English Wikipedia <ref>{{Cite pmid|25171873}}</ref> Architecture of tight junctions and principles of molecular composition #MMPMID25171873 Van Itallie CM; Anderson JM Semin Cell Dev Biol 2014[Dec]; ä (ä): 157-65 PMID25171873show ga The tight junction creates an intercellular barrier limiting paracellular movement of solutes and material across epithelia. Currently many proteins have been identified as components of the tight junction and understanding their architectural organization and interactions is critical to understanding the biology of the barrier. In general the architecture can be conceptualized into compartments with the transmembrane barrier proteins (claudins, occludin, JAM-A, etc.), linked to peripheral scaffolding proteins (such as ZO-1, afadin, MAGI1, etc.) which are in turned linked to actin and microtubules through numerous linkers (cingulin, myosins, protein 4.1, etc.). Within this complex network are associated many signaling proteins that affect the barrier and broader cell functions. The PDZ domain is a commonly used motif to specifically link individual junction protein pairs. Here we review some of the key proteins defining the tight junction and general themes of their organization with the perspective that much will be learned about function by characterizing the detailed architecture and subcompartments within the junction. äArchitecture of tight junctions and principles of molecular compositio(epmc).pdf DeepDyve Pubget Overpricing