Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.gde.2014.05.005 http://scihub22266oqcxt.onion/10.1016/j.gde.2014.05.005 C4254145!4254145!25005742     free     free     free       Curr+Opin+Genet+Dev 2014 ; ä (ä): 24-32 Nephropedia Template TP {{tp|p=25005742|t=2014. Sirtuins, Metabolism, and DNA repair |pdf=|usr=}}{{25005742}} gab.com Text Sirtuins, Metabolism, and DNA repair JO: Curr Opin Genet Dev http://www.kidney.de/pget.php?&tw=1&pmid=25005742 #FOAvip Cells evolve to actively coordinate nutrient availability with cellular activity in order to maintain metabolic homeostasis. In addition, active pathways to repair DNA damage are crucial to avoid deleterious genomic instability. In recent years, it has become increasingly clear that availability of intermediate metabolites may play an important role in DNA repair, suggesting that these two seemingly distant cellular activities may be highly coordinated. The sirtuin family of proteins now described as deacylases (they can also remove acyl groups other than acetyl moieties), it appears to have evolved to control both metabolism and DNA repair. In this review, we discuss recent advances that lay the foundation to understanding the role of sirtuins in these two biological processes, and the potential crosstalk to coordinate them. Twit Text FOAVip Sirtuins, Metabolism, and DNA repair ????Curr Opin Genet Dev http://www.kidney.de/pget.php?&tw=1&pmid=25005742 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25005742 #FOAvip English Wikipedia <ref>{{Cite pmid|25005742}}</ref> Sirtuins, Metabolism, and DNA repair #MMPMID25005742 Choi JE; Mostoslavsky R Curr Opin Genet Dev 2014[Jun]; ä (ä): 24-32 PMID25005742show ga Cells evolve to actively coordinate nutrient availability with cellular activity in order to maintain metabolic homeostasis. In addition, active pathways to repair DNA damage are crucial to avoid deleterious genomic instability. In recent years, it has become increasingly clear that availability of intermediate metabolites may play an important role in DNA repair, suggesting that these two seemingly distant cellular activities may be highly coordinated. The sirtuin family of proteins now described as deacylases (they can also remove acyl groups other than acetyl moieties), it appears to have evolved to control both metabolism and DNA repair. In this review, we discuss recent advances that lay the foundation to understanding the role of sirtuins in these two biological processes, and the potential crosstalk to coordinate them. äSirtuins, Metabolism, and DNA repair (epmc).pdf DeepDyve Pubget Overpricing