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10.1016/j.canlet.2014.08.037 http://scihub22266oqcxt.onion/10.1016/j.canlet.2014.08.037 C4253542!4253542 !25242356     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25242356 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25242356 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cancer+Lett 2014 ; 355 (2 ): 232-41 Nephropedia Template TP {{tp|p=25242356 |t=2014. Fufang Kushen injection inhibits sarcoma growth and tumor-induced hyperalgesia via TRPV1 signaling pathways |pdf=|usr=}}{{25242356 }} gab.com Text Fufang Kushen injection inhibits sarcoma growth and tumor-induced hyperalgesia via TRPV1 signaling pathways JO: Cancer Lett http://www.kidney.de/pget.php?&tw=1&pmid=25242356 #FOAvip Cancer pain is a deleterious consequence of tumor growth and related inflammation. Opioids and anti-inflammatory drugs provide first line treatment for cancer pain, but both are limited by side effects. Fufang Kushen injection (FKI) is GMP produced, traditional Chinese medicine used alone or with chemotherapy to reduce cancer-associated pain. FKI limited mouse sarcoma growth both in vivo and in vitro, in part, by reducing the phosphorylation of ERK and AKT kinases and BAD. FKI inhibited TRPV1 mediated capsaicin-induced ERK phosphorylation and reduced tumor-induced proinflammatory cytokine production. Thus, FKI limited cancer pain both directly by blocking TRPV1 signaling and indirectly by reducing tumor growth. Twit Text FOAVip Fufang Kushen injection inhibits sarcoma growth and tumor-induced hyperalgesia via TRPV1 signaling pathways ????Cancer Lett http://www.kidney.de/pget.php?&tw=1&pmid=25242356 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25242356 #FOAvip English Wikipedia <ref>{{Cite pmid|25242356 }}</ref> Fufang Kushen injection inhibits sarcoma growth and tumor-induced hyperalgesia via TRPV1 signaling pathways #MMPMID25242356 Zhao Z ; Fan H ; Higgins T ; Qi J ; Haines D ; Trivett A ; Oppenheim JJ ; Wei H ; Li J ; Lin H ; Howard OM Cancer Lett 2014[Dec]; 355 (2 ): 232-41 PMID25242356 show ga Cancer pain is a deleterious consequence of tumor growth and related inflammation. Opioids and anti-inflammatory drugs provide first line treatment for cancer pain, but both are limited by side effects. Fufang Kushen injection (FKI) is GMP produced, traditional Chinese medicine used alone or with chemotherapy to reduce cancer-associated pain. FKI limited mouse sarcoma growth both in vivo and in vitro, in part, by reducing the phosphorylation of ERK and AKT kinases and BAD. FKI inhibited TRPV1 mediated capsaicin-induced ERK phosphorylation and reduced tumor-induced proinflammatory cytokine production. Thus, FKI limited cancer pain both directly by blocking TRPV1 signaling and indirectly by reducing tumor growth. |Animals [MESH] |Capsaicin/metabolism [MESH] |Cell Line, Tumor [MESH] |Cytokines/metabolism [MESH] |Drugs, Chinese Herbal/*pharmacology [MESH] |Female [MESH] |Hyperalgesia/*drug therapy/metabolism [MESH] |MAP Kinase Signaling System/*drug effects [MESH] |Mice [MESH] |Mice, Inbred C57BL [MESH] |Phosphorylation/drug effects [MESH] |Proto-Oncogene Proteins c-akt/metabolism [MESH] |Sarcoma/*complications/*drug therapy/enzymology/metabolism [MESH]Fufang Kushen injection inhibits sarcoma growth and tumor-induced hype(epmc).pdf DeepDyve Pubget Overpricing